Project MinE seeks to identify genetic variants that contribute to the development and progression of ALS by analyzing the DNA of a large number of ALS patients and comparing it to healthy controls.
We aim to establish a comprehensive, publicly accessible repository of whole genome sequencing (WGS) data from ALS patients and controls, fostering collaboration and data-sharing across the global research community.
Each working group focuses on a specific aspect of ALS research, collaborating towards shared objectives. Together, we are dedicated to advancing genetic research to uncover new pathways for treating and ultimately curing ALS.
View all working groupsFor a better understanding of the disease a thorough phenotype genotype analysis is needed. This working group will harmonize SOP’s.
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Discover our collaborating centres, the faces driving the change, and the unwavering commitment to defeating ALS.
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The Longitude Prize on ALS, a £7.5 million global challenge, has officially announced its 20 Discovery Award winners. Following a global call to action, these promising teams were chosen from almost 100 entries to receive £100,000 each. Beyond the financial award, these teams have gained access to the most comprehensive ALS patient dataset ever compiled, featuring genomic sequences of 9,000 patients and epigenomics, transcriptomics, and proteomics data for over 2,000 cases. As key data contributor to the Longitude Prize on ALS, Project MinE harmonised previously scattered and heterogeneous whole genome sequencing datasets into a single, coherent and usable joint dataset, enabling a smooth and efficient start for the participating teams.
